Merck, FLAAS-1VL, Adenosine 5′-triphosphate (ATP) disodium salt hydrate

Application
Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:
used as a standard to measure ATP by bioluminescence method
used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
used as a standard in ATP colorimetric assay

Biochem/physiol Actions
Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.
Preparation Note
Each vial contains ~1.2 mg of Na2ATP • 3H2O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.
Prepared to be substantially vanadium-free.