Description
General description
CM Sepharose™ Fast FLow is a weak cation exchanger based on the well established Sepharose™ Fast FLow ion exchange platform, extensively used for preparative protein separations in both research and industrial applications.
Application
CM Sepharose™ Fast FLow is part of the Sepharose™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. It is composed of crosslinked 6% Agarose beads, with carboxymethyl (CM) weak cation exchange groups. CM Sepharose™ Fast FLow has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols. Scale-up with CM Sepharose™ Fast FLow is straight forward and the medium is available in a range of pre-packed process development tools.
As member of the BioProcess media range, CM Sepharose™ Fast FLow meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
Well-proven weak cation exchanger developed for industrial downstream processes
Used extensively for capture and intermediate purification of a wide range of approved biopharmaceuticals
The industry standard for ion exchange chromatography during recent decades
High chemical stability allows for well proven CIP and sanitization protocols
The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.
Preparation Note
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Sepharose is a trademark of Cytiva