General description
Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient, or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration, and cancer. Angiogenesis plays a significant role in tumor growth and metastasis.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 17 analytes in human serum, plasma, and cell culture supernatants.
Analytes included: Angiopoietin-2, BMP-9, EGF, Endoglin, Endothelin-1, FGF-1 (acidic FGF), FGF-2 (basic FGF), Follistatin, G-CSF, HB-EGF, HGF, IL-8, Leptin, PLGF, VEGF-A, VEGF-C and VEGF-D
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Comprehensive 17-Biomarker Analysis: This innovative panel enables the simultaneous quantification of 17 critical angiogenesis and growth factor biomarkers, including Angiopoietin-2, BMP-9, EGF, VEGF-A, and more, providing a holistic view of the angiogenic process.
Versatile Sample Compatibility: Designed for use with human plasma, serum, tissue/cell lysates, and culture supernatants, offering flexibility for a variety of research applications.
Efficient 96-Well Format: Capable of measuring up to 38 samples in duplicate, this format enhances throughput while conserving valuable sample volume, making it ideal for high-volume studies.
Luminex® xMAP® Technology: Utilizes a magnetic bead immunoassay format for fast and sensitive quantification of multiple analytes, ensuring high accuracy and efficiency in your research.
In-Depth Insights into Angiogenesis: By quantifying multiple biomarkers simultaneously, researchers can gain a deeper understanding of the mechanisms regulating blood vessel formation, which is crucial for studying diseases such as cancer, cardiovascular disorders, and diabetic complications.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
