General description
Bone health is regulated by a complex interplay of hormonal, inflammatory, and metabolic signals. This panel—ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), and TNFα—captures key indicators of bone remodeling, endocrine function, and immune activity. These analytes are valuable for studying osteoporosis, arthritis, and metabolic bone diseases, supporting both translational and clinical research in skeletal biology.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in human serum, plasma, or cell/tissue culture supernatants.
Analytes Included: ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), TNFα
Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Features: Targets biomarkers involved in bone remodeling, endocrine regulation, and inflammation
Includes 13 analytes relevant to skeletal health, metabolic activity, and immune signaling
Multiplex format enables simultaneous detection from minimal sample volume
Compatible with human serum, plasma, and cell/tissue culture supernatants
Designed for research in osteoporosis, arthritis, endocrine disorders, and bone metabolism
Benefits: Provides a comprehensive profile of bone turnover and inflammatory biomarkers
Supports investigation of skeletal disease mechanisms and endocrine regulation
Facilitates evaluation of therapeutic interventions and disease progression
Enables high-throughput analysis with reduced sample and reagent use
Delivers reproducible, sensitive results for translational and clinical research
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
