Description
General description
Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in human serum, plasma, and cell culture supernatants.
Analytes included: Cathepsin D, Ferritin, Fibroblast Activation Protein (FAP), Galectin-3, IGFBP3, Melanoma Inhibitory Activty Protein (MIA), Myeloperoxidase (MPO), Sex Hormone Binding Globulin (SHGB)
Note: When IGFBP3 is included in the assay, a larger sample dilution is required. The SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Comprehensive 8-Plex Analyte Kit: This panel facilitates the simultaneous quantification of eight essential biomarkers, including Galectin-3, Cathepsin D, and Fibroblast Activation Protein alpha (FAP), supporting extensive cancer research.
Advanced Luminex® xMAP®Technology: Utilizes a magnetic bead immunoassay approach that allows for quick and sensitive detection of multiple analytes, enhancing laboratory productivity while minimizing sample volume usage.
In-Depth Tumor Biology Insights: By enabling the measurement of multiple circulating biomarkers simultaneously, this panel helps researchers uncover critical insights into tumor biology and the body’s response to cancer.
All-in-One Kit Convenience: The kit is packaged with all necessary components, simplifying the setup process and reducing the potential for errors during preparation.
Recommended Sample Dilution: The assay recommends 25 μL of 1:50 diluted plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well, simplifying sample preparation.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
