Merck, HCL008, ALK-Lung Analyte Control

General description
The ALK-Lung Analyte Control has two cell line cores which demonstrate positive and negative expression of EML4-ALK associated lung cancer.
HistoCyte Laboratories control slides and blocks are made from cultured human cell lines to provide the required range of expression of a specific biomarker. The cell lines are processed using proprietary methods that allow for the creation of a high density embedded cell block with cores that retain their cellular morphology. Available as pre-cut unstained slides or as cell microarray blocks for sectioning.
Application
Ideal for use as a same slide control for immunohistochemistry (IHC) and in situ hybridization (ISH).
The ALK-Lung Analyte Control histology slides have two cell line cores providing positive and negative expression of EML4-ALK. Analyte controls are placed at one end of slide, allowing sample application on same slide for valid comparison.
The ALK-Lung Analyte Control cell microarray block contains two cell line cores that are 2 mm in diameter and between 3.0-3.5 mm in length. The cell microarray block may yield over 300 sections depending on thickness.
Preparation Note
Cell microarray blocks are fixed in 10% neutral buffered formalin and embedded in paraffin wax. Pre-cut unstained slides are prepared from 4 μm thick sections, mounted on positively charged slides, and dried at 37 °C overnight.
Other Notes
For certificates of analysis, contact [email protected].
ALK-Lung Analyte Control brochure is available from HistoCyte Laboratories.