General description
Cytokines, chemokines, and growth factors are key mediators of immune system functions capable of signaling through autocrine, paracrine, and endocrine mechanisms. Their pleiotropic immunomodulatory properties allow these biomolecules to react to diverse stimuli and regulate the immune response, either by promoting or inhibiting inflammation. Growing research continues to highlight the role of the immune system in every facet of human health and disease.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Analyze up to 96 analytes in human serum, plasma, or cell culture supernatant samples.
Included in the 76-Plex Combo Pack: The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel A Magnetic Bead 38-Plex Premixed Panel includes: EGF, Eotaxin/CCL11, G-CSF, GM-CSF, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8/CXCL8, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A/CTLA8, IL-17E/IL-25, IL-17F, IL-18, IL-22, IP-10/CXCL10, MCP-1/CCL2, M-CSF, MIG/CXCL9, MIP-1α/CCL3, MIP-1β/CCL4, PDGF-AA, PDGF-AB/BB, RANTES/CCL5, TNFα, TNFβ/LTA, VEGF-A. RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.
The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead 38-Plex Premixed Panel includes: 6Ckine, sCD137, sFAS, sFASL, APRIL, BAFF, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, Granzyme A, Granzyme B, HMGB1, I-309, IFNβ, IFNψ, IL-16, IL-20, IL-21, IL-23, IL-28A, IL-29, IL-31, IL-33, I-TAC, LIF, MCP-2, MCP-4, MIP-1δ, MIP-3α, Perforin, SCF, SDF-1, TARC, TPO, TRAIL, TSLP.
Included in the 96-plex Combo Pack: The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel A 48-plex kit includes: sCD40L, EGF, Eotaxin/CCL11, FGF-2/FGF-basic, FLT-3L, Fractalkine/CX3CL1, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A/CTLA8, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10/CXCL10, MCP-1/CCL2, MCP-3/CCL7, M-CSF, MDC, MIG/CXCL9, MIP-1α/CCL3, MIP-1β/CCL4, PDGF-AA, PDGF-AB/BB, RANTES/CCL5, TGFα, TNFα, TNFβ/LTA, VEGF-A. RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.
The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B Panel 48-plex kit includes: 6Ckine, sCD137, sFAS, sFASL, APRIL, BAFF, BCA-1, CCL28, CTACK, CXCL16, ENA-78, Eotaxin-2, Eotaxin-3, GCP-2, Granzyme A, Granzyme B, HMGB1, I-309, IFNβ, IFNψ, IL-11, IL-16, IL-20, IL-21, IL-23, IL-24, IL-28A, IL-29, IL-31, IL-33, IL-34, IL-35, I-TAC, LIF, Lymphotactin, MCP-2, MCP-4, MIP-1δ, MIP-3α, MIP-3β, MPIF-1, Perforin, SCF, SDF-1, TARC, TPO, TRAIL, TSLP.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
High-Plex Capability: Includes MILLIPLEX® Panels A and B, which are analyzed independently but allow cross-panel data integration for a total of up to 96 analytes for a holistic view of immune biomarkers.
Comprehensive Insights: Study immune modulation across inflammation, autoimmune mechanisms, and disease pathways with a broad biomarker panel.
Premixed Convenience: Ready-to-use magnetic bead panels reduce preparation time and ensure consistency.
Cross-Study Flexibility: Use individual panels for focused hypotheses or combo packs for exploratory research.
xMAP® Technology Compatibility: Leverage Luminex®’s platform for high-throughput, reproducible multiplex detection.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
