Description
General description
Inflammatory cascades in the brain are shaped by acute phase proteins and complement activity. CRP and SAP accumulate in amyloid plaques and signal systemic inflammation. α1-Antitrypsin tempers protease activity and may dampen microglial overactivation, offering a protective buffer against amyloid-beta toxicity. PEDF contributes neuroprotective and anti-angiogenic effects, while complement C4 supports immune surveillance and debris clearance in neurodegenerative contexts.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in human serum, plasma, and cerebrospinal fluid (CSF).
Analytes included: CRP, α1-antitrypsin, PEDF, SAP, MIP-4, Complement C4.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Acute Phase Response Profiling: Simultaneously quantify CRP, SAP, and α1-antitrypsin to capture comprehensive inflammatory responses and immune system activation patterns critical for neurodegeneration research.
Sample Type Flexibility: Analyze serum, plasma, and cerebrospinal fluid samples with validated performance, enabling comprehensive biomarker studies across diverse biological specimens and research applications.
Batch-to-Batch Consistency: Trust in stringent manufacturing standards and quality controls that ensure reproducible results across different kit lots, supporting longitudinal studies and multi-site collaborations.
Expert Scientific Partnership: Access dedicated field application scientists and technical support teams who provide can specialized multiplex assay guidance.
Configurable Research Solutions: Design your ideal biomarker panel by selecting any combination of the 6 analytes, creating tailored assays that perfectly align with your specific research hypotheses and objectives.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
