Description
General description
Neurodegeneration often reflects a breakdown in cellular communication and vascular health. BDNF, a vital neurotrophic factor, underpins neuronal survival and adaptability, with diminished levels tied to Alzheimer′s and stroke. Vascular adhesion molecules sICAM-1 and sVCAM-1 reveal inflammation and blood-brain barrier compromise. PDGF isoforms promote vascular repair and neuronal resilience, while immune markers like RANTES, MPO, and cathepsin D highlight ongoing tissue damage and immune activation.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 10 analytes in human serum, plasma, and cerebrospinal fluid (CSF).
Analytes included: BDNF, Cathepsin D, sICAM-1, MPO, PDGF-AA, RANTES, NCAM, PDGF-AB/BB, sVCAM-1, PAI-1(total).
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Mutiplex Discovery Power: Simultaneously quantify a diverse array of biomarkers from neurotrophic factors to inflammatory mediators, providing unprecedented breadth of neurobiological insight in a single multiplex assay.
Configurable Panel Flexibility: Design your ideal research solution by selecting any combination of the 10 available analytes to create a configured kit that perfectly matches your specific research objectives and hypotheses.
All-in-One Convenience: Receive complete assurance with our comprehensive box format containing all necessary reagents, eliminating procurement delays and ensuring seamless experimental execution from start to finish.
Cross-Matrix Compatibility: Analyze serum, plasma, and cerebrospinal fluid samples with validated performance, maximizing sample utility and enabling comprehensive biomarker profiling across diverse biological specimens.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
