Merck, I7508-500G, myo-Inositol

General description
Myo-Inositol, also known as i-Inositol, is a sugar alcohol and functions as a growth factor for both animals and microorganisms. Classified as a pseudovitamin, it doesn′t meet the essential vitamin criteria, as its deficiency doesn′t lead to disease conditions despite its vital role in the body. This polyol is abundantly present and serves as a structural element in eukaryotic cell secondary messengers, playing crucial roles in biological processes like insulin signal transduction and cytoskeleton transduction.

Myo-Inositol, a key component in structural lipids like phosphatidylinositol (PI) and its various phosphates, including phosphatidylinositol phosphate (PIP) lipids. It plays the role of an osmolyte, cell culture media supplement, nutrient, phosphoinositide phospholipase C inhibitor, and metabolite. It participates in cell signaling, potentially stimulating tumor cell differentiation, and is found in cell membrane phospholipids, plasma lipoproteins, and the nucleus, showcasing potential chemopreventive properties. Myo-Inositol is a versatile compound that finds application in cell culture, metabolomics and biochemical research, contributing to the exploration of cellular processes and their impact on health and disease.
myo-Inositol (MI) is a sugar-like molecule present primarily in the glial cells of the human brain.
Application
myo-Inositol has been used:
in the liquid basal medium as a control for the inositol starvation of cultures
as a supplement in synthetic oviduct fluid medium for embryo culture
as a component of Fuji vitamin solution to prepare nutritive medium for the growth of sugarcane plantlets

Biochem/physiol Actions
A component of membrane phospholipids, glycosyl­phosphatidyl­inositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers.
myo-Inositol (MI) serves as an osmolyte, and it aids the formation of the cell membrane and myelin sheet structures. It functions as a crucial precursor of membrane phospho-inositides and phospholipids. Elevated concentration of myo-Inositol (MI) is observed in several brain disorders such as Alzheimer′s disease, gliomatosis cerebri, and diabetes mellitus. Myo-Inositol is a constituent of membrane phospholipids, glycosylphosphatidylinositol anchors that can bind glycoproteins to cell membranes, and inositol phosphate second messengers.
Features and Benefits
Ideal for Cell Biology, Metabolomics and Biochemical research
Versatile and adaptable for wide variety of laboratory and research applications

Other Notes
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