Merck, L5142-1MG, Lectin from Triticum vulgaris (wheat)

General description
Wheat germ lectin (WGA) from Triticum vulgaris exists as a homodimer and has multiple N-acetyl glucosamine (GlcNAc) binding sites. It is resistant to protein denaturation agents and is used for the detection of O-GlcNAc proteins. WGA binding to N-glycolylneuraminic acid (Neu5Ac) may modulate pro-inflammatory immune response.
Application
Lectin from Triticum vulgaris (wheat) has been used:
in lectin binding assay of samples from intrauterine stages of filarial parasites
in the histological studies of mice myocytes
for the generation bead-biotin-WGA complex with Dynabeads® M-280 Streptavidin magnetic beads for lectin magnetic separation of Toxoplasma gondii oocytes from water samples

Biochem/physiol Actions
WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.
Packaging
Package size based on protein content.
Physical form
Contains sodium citrate
Preparation Note
Conjugates are prepared from affinity purified lectin.
Legal Information
Dynabeads is a registered trademark of Invitrogen Dynal AS Corp