Description
General description
Adipokines such as insulin, leptin, resistin, adiponectin, IL-6, TNF-α, MCP-1, and PAI-1 are key regulators of energy metabolism, inflammation, and endocrine signaling. Insulin facilitates glucose uptake, leptin controls appetite and energy balance, and resistin is linked to insulin resistance. Adiponectin enhances insulin sensitivity, while IL-6 and TNF-α are central to obesity-related inflammation. MCP-1 recruits immune cells to adipose tissue, and PAI-1 influences fibrinolysis and metabolic dysfunction. Together, these biomarkers offer a comprehensive view of adipose tissue function and its systemic impact on metabolic health.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum or plasma samples.
Analytes included: Insulin, Leptin, Resistin, Adiponectin, IL-6, TNF-α, MCP-1, PAI-1 (Total)
Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy
Features and Benefits
Features:
Measures key adipokines and cytokines involved in metabolic regulation and inflammation
Includes analytes such as insulin, leptin, resistin, adiponectin, IL-6, TNF-α, MCP-1, and PAI-1 (Total)
Enables multiplex detection for efficient and simultaneous analysis
Compatible with mouse serum, plasma, and tissue culture supernatant samples
Designed for use in metabolic, obesity, and inflammation-related research
Benefits:
Provides a comprehensive profile of adipose tissue function and systemic metabolic health
Supports early identification of insulin resistance, obesity-related inflammation, and metabolic dysfunction
Facilitates evaluation of therapeutic interventions targeting adipokine pathways
Enhances understanding of endocrine and immune interactions in preclinical models
Streamlines experimental workflows with high-throughput, multi-analyte capability
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
