Merck, N1638-100ML, Nystatin Suspension

Name: Nystatin Suspension
Brand: Merck
SKU: N1638-100ML

Size:100 mL, Fungicidin, Mycostatin, suspension, 10, 000 unit/mL in DPBS, BioReagent, suitable for cell culture

Available Catalog Numbers

N1638-100ML N1638-20ML

Catalog Number: N1638-100ML

Pricing

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Category

Antibiotics & Antimycotics

Pack Size100 mL

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Antibiotics

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Chemical structure: polyene
Application
Nystatin suspension has been used:

to inhibit caveolin-mediated endocytosis
as a component of Eagle′s minimum essential medium (EMEM)
to enumerate lactic acid bacteria (LAB)
in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.
Biochem/physiol Actions
Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.
Preparation Note
It is 0.1μ filtered and cell culture tested.
Other Notes
Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Disclaimer
This product is stable at 37°C for three days.

Specifications

General

UNSPSC Code	12352207
PubChem Substance ID	24897511
NACRES	NA.76
Web Name Suffix Override	suspension, non-animal origin, suitable for cell culture, BioReagent
SMILES string	C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
InChI	1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
InChI key	VQOXZBDYSJBXMA-QEKUPDCNSA-N
product line	BioReagent
form	suspension
concentration	10,000 unit/mL in DPBS
technique(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested
color	yellow

Ordering

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Merck, N1638-100ML, Nystatin Suspension

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