Merck, P1639-5MG, Patulin

General description
Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na⁺-K⁺ dependent ATPase and to induce intra- and intermolecular protein crosslinking.
Application
Patulin has been used:
to study patulin contamination of bottled wine
in DNA-damaging activity of patulin in Escherichia coli
in molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus

Biochem/physiol Actions
Mycotoxin with anti-bacterial, potassium uptake inhibitory, and possibly carcinogenic activities. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na⁺-K⁺ dependent ATPase and to induce intra- and intermolecular protein crosslinking.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.