Description
General description
Adiponectin, leptin, and PAI-1 are key regulators of metabolism and insulin sensitivity, while IL-1β, IL-6, TNFα, and MCP-1/CCL2 are central to adipose tissue inflammation. Together, these biomarkers provide insight into metabolic dysfunction and immune-adipocyte interactions in rat models of obesity and related disorders.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat cell culture supernatants.
Analytes Included: Adiponectin, IL-1β, IL-6, Leptin, MCP-1/CCL2, PAI-1 (total), TNFα
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Features:
Multiplex detection of 7 adipokines and cytokines in a single assay
Magnetic bead-based format for efficient and reproducible processing
Compatible with rat serum, plasma, and tissue lysates
High sensitivity for low-abundance biomarkers
Utilizes Luminex® xMAP technology for high-throughput analysis
Short assay time (~4.5 hours) with minimal hands-on steps
Benefits:
Saves time and sample volume through multiplexing
Reduces assay variability and improves data quality
Enables comprehensive profiling of adipocyte-related biomarkers
Supports research in obesity, diabetes, and metabolic syndrome
Facilitates translational studies in rat models of metabolic disease
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
