Description
General description
KIM-1, Clusterin, and GSTα are sensitive indicators of tubular injury and cellular stress. IP-10/CXCL10 and TIMP-1 reflect renal inflammation and tissue remodeling. OPN and VEGF-A are involved in fibrosis and vascular responses. Together, these biomarkers offer a comprehensive view of kidney toxicity and repair mechanisms in rat models.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat urine samples.
Analytes Included: Clusterin, GSTα, IP-10/CXCL10, KIM-1, Osteopontin (OPN), TIMP-1, VEGF-A Note: GSTα is in a competitive assay format.
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Features: Multiplex detection of 7 kidney injury biomarkers in one assay
Magnetic bead-based format for efficient and reproducible processing
Compatible with urine samples
High sensitivity for early detection of renal damage
Benefits: Conserves sample volume and reagents through multiplexing
Improves data quality and reproducibility with magnetic bead format
Enables early detection and monitoring of kidney injury
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.