Description
General description
This panel includes key hormones and cytokines involved in regulating glucose metabolism, appetite, insulin signaling, and inflammatory responses. Analytes such as insulin, leptin, ghrelin, GLP-1, and glucagon play central roles in energy balance and metabolic homeostasis, while cytokines like IL-6 and TNFα provide insight into inflammation-linked metabolic dysfunction. Measuring these biomarkers supports research in obesity, diabetes, appetite regulation, and metabolic syndrome in rodent models.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 14 analytes in rat serum, plasma, or cell culture supernantants.
Analytes Included: Amylin (active), C-Peptide 2, Ghrelin (active), GIP (total), GLP-1 (active), GLP-1 (total), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total), Secretin, TNFα
Note: GLP-1 (Active) and GLP-1 (Total) cannot be run together in the same assay. Protease inhibitors should be added upon collection of samples.
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Features:
Measures 15 metabolic and appetite-related biomarkers in one assay
Suitable for serum, plasma, and tissue lysates
High sensitivity and specificity for low-abundance hormones
Multiplex format reduces sample volume and assay time
Benefits:
Enables comprehensive profiling of metabolic and inflammatory pathways
Supports research in obesity, diabetes, and energy regulation
Saves time and resources compared to single-analyte assays
Provides reliable data for rodent model studies
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
