Merck, S3523-50MG, Surfactin

Name: Surfactin
Brand: Merck
SKU: S3523-50MG

Size:50 mg, surfactin C, from Bacillus subtilis, ≥98.0% (HPLC)

Available Catalog Numbers

S3523-10MG S3523-50MG

Catalog Number: S3523-50MG

Pricing

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Category

Antibiotics & Antimycotics

Pack Size50 mg

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Antibiotics

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Chemical structure: peptide
Application
Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.
Biochem/physiol Actions
Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Specifications

General

UNSPSC Code	51102829
PubChem Substance ID	24899562
NACRES	NA.85
SMILES string	CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
InChI	1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
InChI key	NJGWOFRZMQRKHT-WGVNQGGSSA-N
biological source	Bacillus subtilis
description	zwitterionic
assay	≥98.0% (HPLC)
form	powder
storage condition	(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color	white to faint yellow
CMC	7.5-20 μmol/L (depending on methods)
solubility	ethanol: soluble 10 mg/mL
antibiotic activity spectrum	Gram-negative bacteria

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Merck, S3523-50MG, Surfactin

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General

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