Merck, SAB4200877-25UL, Anti-MAP1b antibody, Mouse monoclonal

General description
MAP1b is the major microtubule associated protein in developing brain which changes its expression during development. In the newborn rat brain, it is a major component of microtubules but in the adult its level is ten-fold lower.1 This change in the level of expression occurs simultaneously with neuronal maturation
Application
The antibody may be used in various immunochemical techniques including immunohistology and Immunoblotting.
Biochem/physiol Actions
MAP1b is the first MAP to appear in growing axons during development as it is present from the first emergence of the nascent axon from the cell body.4
Monoclonal Anti-MAP1b antibody is immunospecific for MAP1b (also known as MAP5, MAPIX or MAP1.2)1,2 Monoclonal Anti-MAP1b reacts with human, rat, mouse, bovine, hamster, chicken and cat tissue or cells. Monoclonal Anti-MAP1b does not react with tubulin of other microtubule associated proteins.
Physical form
Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.
Preparation Note
For continuous use, store at 2-8°C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer
This product is for R&D use only, not for drug, household, or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.