Merck, SRE0023-50ML, β-Glucuronidase from abalone

Name: β-Glucuronidase from abalone
Brand: Merck
SKU: SRE0023-50ML

Size:50 mL, Purified, aqueous solution, β-glucuronidase 150, 000-250, 000 units/mL, β-glucuronidase ≥20, 000, 000 units/g protein

Available Catalog Numbers

SRE0023-10ML SRE0023-25ML SRE0023-50ML

Catalog Number: SRE0023-50ML

Pricing

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Category

Recombinant Enzymes

Pack Size50 mL

TagsProtein Biology Proteins & Enzymes Drug Analysis Enzymes

CollectionsMerck Proteins & Enzymes: Nucleases, Albumins & High‑Purity Enzymes Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Application
Technical Article Comparing Performance of Different Enzymes
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine.
Biochem/physiol Actions
β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.
Physical form
Supplied as an aqueous solution containing L-proline, ammonium acetate and sodium azide
Other Notes
One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay).

Specifications

General

UNSPSC Code	12352204
NACRES	NA.54
Enzyme Commission (EC) Number	3.1.2.31 ( BRENDA \| IUBMB )
MDL number	MFCD00130629
form	aqueous solution
β-glucuronidase activity	≥20,000,000 units/g protein
secondary activity	≤7,500 units/mL sulfatase
storage temp.	2-8°C
Quality Level	200

Ordering

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