Merck, SRE0029-50MG, Cardiolipin solution from bovine heart

Application

Site of action of the local anesthetic tetracaine in a phosphatidylcholine bilayer with incorporated cardiolipin.: This paper examines how tetracaine interacts with phosphatidylcholine bilayers containing cardiolipin, which has implications for understanding local anesthetic mechanisms (Shibata et al., 1995).

Biochem/physiol Actions
Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component and can inhibit cell attachment of fibronectin, vitronectin, and type I collagen.
Physical form
Approximately 5 mg/ml in ethanol.
Other Notes
>80% polyunsaturated fatty acid content, primarily linoleic acid.
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.