Merck, T111050-10G, DMT-dT Phosphoramidite

Name: DMT-dT Phosphoramidite
Brand: Merck
SKU: T111050-10G

Size:10 g, 5′-O-(4, 4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N, N′-diisopropylphosphoramidite], 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxythymidine, 3′-[2-cyanoethyl N, N-bis(1-methylethyl)phosphoramidite], DMT-dT amidite, Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N, N-bis(1-methylethyl)phosphoramidite], configured for ÄKTA® and OligoPilot®

Available Catalog Numbers

T111050-10G T111050-5G T111050-6X5G

Catalog Number: T111050-10G

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Category

Nucleotides & Nucleosides

Pack Size10 g

TagsChemistry & Biochemicals Biochemicals Nucleosides & Nucleotides

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)). Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides. DMT-dT Phosphoramidite belongs to ÄKTA® synthesizers.
Legal Information
OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva

Specifications

General

nucleoside profile
NACRES	NA.51
PubChem Substance ID	329826647
UNSPSC Code	41116107
MDL number	MFCD00055063
InChI	1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/m0/s1
SMILES string	COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
InChI key	UNOTXUFIWPRZJX-CEXSRUIHSA-N
biological source	non-animal source (no BSE/TSE risk)
type	for DNA synthesis
product line	Proligo Reagents
assay	≥99% (31P-NMR)
form	powder or granules
technique(s)	oligo synthesis: suitable
impurities	≤0.3 wt. % water content (Karl Fischer)
color	white to off-white
<i>λ</i>	conforms (UV/VIS Identity)
compatibility	configured for ÄKTA® and OligoPilot®

Ordering

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Merck, T111050-10G, DMT-dT Phosphoramidite

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