Merck, T6134-25G, Tylosin tartrate

Name: Tylosin tartrate
Brand: Merck
SKU: T6134-25G

Size:25 g, [R-(R′R′)]-2, 3-Dihydroxybutanedionate Tylosin salt, potency: ≥800 units/mg tylosin

Available Catalog Numbers

T6134-25G T6134-5G

Catalog Number: T6134-25G

Pricing

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Category

Antibiotics & Antimycotics

Pack Size25 g

TagsChemistry & Biochemicals Biochemicals Antibiotics

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/T6134

Description

General description
Chemical structure: macrolide
Application
Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticum and Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.
Biochem/physiol Actions
Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
This product is a mixture of tylosin A, B, C, and D tartrates.
Disclaimer
Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

Specifications

General

antibiotic activity spectrum
NACRES	NA.85
PubChem Substance ID	24900350
UNSPSC Code	51283225
MDL number	MFCD07783824
InChI	1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
SMILES string	O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
InChI key	ICVKYYINQHWDLM-KBEWXLTPSA-N
form	powder
potency	≥800 units/mg tylosin
storage condition	(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color	off-white to yellow
solubility	H2O: soluble 50 mg/mL

Ordering

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Merck, T6134-25G, Tylosin tartrate

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