Description
Quantity: 25 g
Packaging: Plastic Bottle
Unit Size: Each
General Description • 4-Aminobutyric acid is a γ-amino acid and monocarboxylic acid derived from butyric acid• It is an amino acid that shows inhibitory activities against neurotransmitters, including GABA, and acts by binding GABA-A receptor and inhibiting the activity of signal-receiving neurons• This compound, converted from neurotransmitter glutamate, is essential to regulate neuronal excitability• It binds to GABA-A and GABA-B receptors, causing ion channel opening, hyperpolarization, and eventually inhibition of neurotransmissionApplications• 4-Aminobutyric acid has been used in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for immunohistochemical experiments• It is used, in vivo, to detect GABA neurotransmitter by magnetic resonance spectroscopy• This compound increases the production of short-chain fatty acids and decreases pH values in mouse colon• Some in vivo experiments, using rats, mice, and pigs, demonstrated that 4-Aminobutyric acid can modulate intestinal fluid secretion, blood flow and ulceration
