Thermo Fisher, 28105-254630, Hypersil™ BDS C18 Columns

Hypersil™ BDS C18 Column 250 × 4.6 mm, 5 µm is used for general-purpose reversed-phase HPLC separations of small molecules. The column contains spherical, fully porous, base-deactivated silica bonded with C18 chemistry and is endcapped to reduce unwanted silanol interactions. This analytical format has a 250 mm length, 4.6 mm internal diameter, 5 µm particle size and 130 Å pore size. The stationary phase has approximately 11% carbon loading and operates over a stated pH range of 2 to 8, with a maximum pressure rating of 5800 psi. The base-deactivated surface helps improve peak shape for basic analytes while maintaining broad utility for routine QA/QC and method work. Its conventional 4.6 mm internal diameter and 250 mm length make it suitable for established HPLC methods requiring robust C18 selectivity and reproducible retention.