Thermo Fisher, 30005-254630, Hypersil™ Silica HPLC Columns

Hypersil™ Silica is a normal-phase HPLC column for separation of nonpolar to moderately polar organic compounds. This configuration uses 5 µm fully porous silica in a 4.6 × 250 mm analytical column. Unbonded silica provides polar surface interactions that support normal-phase retention and can be useful for analytes that are poorly resolved by conventional reversed-phase methods. The phase is commonly applied to lipids, steroids, aromatic compounds, and other compounds whose selectivity depends on adsorption to silica. The column is intended for conventional HPLC operation with compatible nonaqueous or low-water mobile phases. The 250 mm length provides high resolving power for methods that require greater separation efficiency.