Thermo Fisher, 455490010, Amphotericin B, 85%

Name: Amphotericin B, 85%
Brand: Thermo Fisher
SKU: 455490010

Quantity: 1 g, Unit Size: Each, This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Catalog Number: 455490010

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Category

Hormones for Cell Culture

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 1 g
Unit Size: Each
General Description• Amphotericin B is an antibiotic that has antifungal activity and is produced mainly by Streptomyces nodosusApplications • It has antifungal activity against fungus caused by protozoan parasites of Leishmania genus by binding to an essential component of the fungal cell membrane and altering cell membrane permeability• It can suppress bone marrow progenitor cells and induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro

Specifications

General

CAS	1397-89-3
Chemical Name or Material	Amphotericin B
Formula Weight	924.09
Health Hazard 1	<b>Warning</b>
Health Hazard 2	<b>GHS H Statement</b> Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Health Hazard 3	<b>GHS P Statement</b> Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IUPAC Name	(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
InChI Key	APKFDSVGJQXUKY-ZNVUZQDLSA-N
MDL Number	MFCD00877763
Melting Point	>170.0°C
Molecular Formula	C47H73NO17
PubChem CID	134129663
SMILES	C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(O)=O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C/C=C\C=C/C=C\C=C/C=C\C=C/2)[C@@H](O)[C@@H](N)[C@@H]1O

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Thermo Fisher, 455490010, Amphotericin B, 85%

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