Thermo Fisher, A18512.14, 4-Nitrobenzenesulfonyl chloride, 97%

Name: 4-Nitrobenzenesulfonyl chloride, 97%
Brand: Thermo Fisher
SKU: A18512.14

Quantity: 25 g, Unit Size: Each, 4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N, N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines

Catalog Number: A18512.14

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Category

Amines

Pack Size25 g

TagsChemicals Organic compounds Sulfonyl halides

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 25 g
Unit Size: Each
Applications4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N,N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines of sulfadiazine, sulfamethoxazole and [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2′-bipyridine, nbs = 4-nitrobenzenesulfonate).SolubilitySoluble in toluene, tetrahydrofuran, methylene chloride and ethyl acetate. Insoluble in water.NotesMoisture sensitive. Incompatible with strong oxidizing agents and strong bases.

Specifications

General

Beilstein	746543
CAS	98-74-8
Chemical Name or Material	4-Nitrobenzenesulfonyl chloride
DOT Information	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECS Number	202-697-9
Formula Weight	221.62
Health Hazard 1	H314
Health Hazard 2	<b>GHS H Statement</b><br />H314-H318<br />Causes severe skin burns and eye damage.<br />Causes serious eye damage.
Health Hazard 3	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
IUPAC Name	4-nitrobenzenesulfonyl chloride
InChI Key	JXRGUPLJCCDGKG-UHFFFAOYSA-N
MDL Number	MFCD00007445
Melting Point	76°C to 80°C
Molecular Formula	C6H4ClNO4S
PubChem CID	7404
Recommended Storage	Ambient temperatures; Store under Nitrogen
SMILES	[O-][N+](=O)C1=CC=C(C=C1)S(Cl)(=O)=O
Sensitivity	Moisture sensitive
Solubility Information	Soluble in toluene,tetrahydrofuran,methylene chloride and ethyl acetate. Insoluble in water.

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Thermo Fisher, A18512.14, 4-Nitrobenzenesulfonyl chloride, 97%

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