Thermo Fisher, A18512.22, 4-Nitrobenzenesulfonyl chloride, 97%

Name: 4-Nitrobenzenesulfonyl chloride, 97%
Brand: Thermo Fisher
SKU: A18512.22

Quantity: 100 g, Unit Size: Each, 4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N, N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines

Catalog Number: A18512.22

Pricing

Send an RFQ.

View RFQ List

Category

Amines

Pack Size100 g

TagsChemicals Organic compounds Sulfonyl halides

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 100 g
Unit Size: Each
Applications4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N,N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines of sulfadiazine, sulfamethoxazole and [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2′-bipyridine, nbs = 4-nitrobenzenesulfonate).SolubilitySoluble in toluene, tetrahydrofuran, methylene chloride and ethyl acetate. Insoluble in water.NotesMoisture sensitive. Incompatible with strong oxidizing agents and strong bases.

Specifications

General

Beilstein	746543
CAS	98-74-8
Chemical Name or Material	4-Nitrobenzenesulfonyl chloride
DOT Information	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECS Number	202-697-9
Formula Weight	221.62
Health Hazard 1	H314
Health Hazard 2	<b>GHS H Statement</b><br />H314-H318<br />Causes severe skin burns and eye damage.<br />Causes serious eye damage.
Health Hazard 3	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
IUPAC Name	4-nitrobenzene-1-sulfonyl chloride
InChI Key	JXRGUPLJCCDGKG-UHFFFAOYSA-N
MDL Number	MFCD00007445
Melting Point	76°C to 80°C
Molecular Formula	C6H4ClNO4S
PubChem CID	7404
Recommended Storage	Ambient temperatures; Store under Nitrogen
SMILES	[O-][N+](=O)C1=CC=C(C=C1)S(Cl)(=O)=O
Sensitivity	Moisture sensitive
Solubility Information	Soluble in toluene,tetrahydrofuran,methylene chloride and ethyl acetate. Insoluble in water.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Thermo Fisher, A18512.22, 4-Nitrobenzenesulfonyl chloride, 97%

Send an RFQ.

General

Notice

More from Thermo Fisher.

NaCl (5 M), RNase-free, 100 mL

Potassium Acetate (3 M), pH 5.5, RNase-free

SDS, 20% Solution, RNase-free

RNase A, DNase and protease-free (10 mg/mL)

More from Thermo Fisher.

NaCl (5 M), RNase-free, 100 mL

Potassium Acetate (3 M), pH 5.5, RNase-free

SDS, 20% Solution, RNase-free

RNase A, DNase and protease-free (10 mg/mL)