Thermo Fisher, A30148, <i>Silencer</i>™ Select Human Long Non-coding RNA (lncRNA) siRNA Library, 1 set (96-well)

Format: 96-well Plate
Unit Size: Each
• Long noncoding RNAs (lncRNAs) have gained interest in recent years as they have been implicated in genomic regulation, cellular housekeeping functions, developmental processes, and disease
• TheSilencer™ Select Human Long Noncoding RNA (lncRNA) siRNA Library contains 15,081 Ambion™SilencerSelect siRNAs targeting 5,027 lncRNAs as identified in GENCODE v22
• Library is designed against targeted transcripts aligned to the entire genome, maximizing prediction and coverage across alternatively spliced transcripts
• SilencerSelect siRNAs are designed with Thermo Fisher Scientific’s leading design algorithms and locked nucleic acid (LNA) chemical modifications
• This helps ensure efficacy, specificity, and potency to provide a powerful platform for achieving accurate and consistent phenotype data from RNAi screens in the discovery and elucidation of lncRNAs
• Superior efficacy – Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
• Highest efficiency – Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
• Dependable – Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
• Convenient – Reduce data de-convolution and accelerate target validation with our 96- and 384-well arrayed format
• Customizable – Choose the best option for workflow demands, including additional siRNA scales and pooled formats
• Contains 0.25 nmol of each highly potent siRNA, sufficient for at least 500 transfections (at 5 nM siRNA, 100 μL transfection volume)