Description
Includes: BioPharma Finder 5.4
Unit Size: Each
Workflow-driven characterization, method processing, and result reviewPeptide mapping workflow:
• Validate amino acid assignments with a novel MS2 prediction algorithm, providing an added layer of certainty to confirm the accuracy of the amino acid sequence
• Characterize site-specific expected and unknown post-translational modifications (PTMs), and utilize error-tolerant searches to identify unexpected modifications
• Map disulfide bonds, create de novo sequence searches, and accurately detect low-level impurities and sequence variants for comprehensive analysis
• Experience streamlined processes, including the Multi-Attribute Method (MAM) workflow to span from discovery peptide mapping to critical quality attributes (CQAs) monitoring in GMP environmentsOligonucleotide workflow:
• Automated annotation and confirmation of oligonucleotide sequence with a novel MS2 prediction algorithm
• Construct oligonucleotide sequences with built in customized building block subunits, including base, backbone linker, 2' ribose, 3' terminal and 5' terminalIntact protein workflow:
• Rapidly measure the intact molecular weight of biotherapeutics, including proteins and oligonucleotides, with built in deconvolution algorithms
• Protein sequence matching to annotate N-linked glycosylations and common modifications
• Confident identification of Antibody Drug Conjugates (ADC) and Drug Antibody Ratio (DAR) determination using sliding window algorithmTop down workflow:
• Features a simple workflow for sequencing intact protein molecules using ProSightBP as the core algorithm
• Includes multiple raw file comparison with combined interactive fragmentation coverage maps
• Supports multiple modes of fragmentation CID, HCD, ETD, EThcD and UVPDArdia Platform:
• Features: Reporting, data security, collaboration
