Description
Flow Rate: 6 to 1980 L/hr.
Unit Size: Each
The system can be tailored for a specific process and flow rate(s) through the selection of low pulsation pumps, offered in three pump combinations, matched fluid transfer assembly sizes, and single-use valve block flow paths aligned with the fluid transfer assemblies. The novel single-use valve manifold design removes limitations caused by pinch valves or clam shell/liner designs, provides error-free fluid transfer assembly insertion, and enables up/down column flow, ensuring safe operation while providing a quicker turn-around time in process suites. The DynaChrom Chromatography System is designed to be column agnostic and can work with any end-user-selected column.Packaged with our TruChrom software, the DynaChrom Chromatography System provides the ability to leverage existing site DeltaV network infrastructure and allows ease of tech transfer, data integration, and data storage. The system enables meeting of regulatory requirements for use in cGMP and CFR 21 Part 11 compliant processes. The use of robust components helps ensure reliable and consistent results. Modular design and simplified options help ensure scalability from process development to commercial production.Features of the DynaChrom Chromatography System include:
• Unique manifold designEasy and error-free fluid transfer assembly insertionNo-pinch-valve designEnables up/down column flow
• Wide operational flow rangeFlowrates from 1 L/hr to 1,980 L/hr depending on pump(s) selectedFluid transfer assemblies in 1/4-, 3/8-, 1/2-, and 3/4-inch sizesLow pulsation pumps
• Zero void volume/ring flushPrevious phase liquids are instantly flushed at the start of the next phaseReduced buffer useImproved peak resolution and product yield
• Built on the Emerson DeltaV automation platformEase of tech transfer and data integrationAbility to leverage existing DeltaV network infrastructureCapable of running processes in batch mode
• Chromatography steps and modes of operationAffinity, Anion Exchange (AEX), Cation Exchange (CEX), or Reversed Phased Chromatography (RPC)Can be configured for bind/elute or flow-through modes of operationCan support in-line dilutionApplications of the DynaChrom Chromatography System include:
• Monoclonal antibody and viral vector production
