Thermo Fisher, G22183, Guanosine 5'-<i>O</i>-(3-Thiotriphosphate), BODIPY™ FL Thioester, Sodium Salt (BODIPY™ FL GTP-γ-S, Thioester)

Name: Guanosine 5'- O -(3-Thiotriphosphate), BODIPY™ FL Thioester, Sodium Salt (BODIPY™ FL GTP-γ-S, Thioester)
Brand: Thermo Fisher
SKU: G22183

Quantity: 50 μL, Unit Size: Each

Catalog Number: G22183

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Category

Nucleic Acid Stains

Pack Size50 µL

TagsNucleotides Nucleic Acid Synthesis

CollectionsThermo Fisher Nucleic Acid Synthesis Reagents for Oligo Manufacturing Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 50 μL
Unit Size: Each
BODIPY FL GTP-γ-S binds to GTP-binding proteins. To create this fluorescent nucleotide, the BODIPY FL fluorophore was linked through the γ-thiol of GTP-γ-S. The fluorescence of BODIPY FL GTP-γ-S is quenched approx. 90% relative to that of the free dye, but may be recovered on binding to G-proteins. In addition to its potential use for binding studies, the BODIPY FL GTP-γ-S thioether is an important new substrate for Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins.Drug Discovery and Development, Enzyme and Protein Activity Assays, Phosphatase Activity, Phosphatase Biology, Proteins, Expression, Isolation and Analysis, Target and Lead Identification and Validation

Specifications

General

Labeling Method	Chemical Labeling, Direct Labeling
Label or Dye	BODIPY™ FL
Product Type	Guanosine 5'-O
Quantity	50 μL
Shipping Condition	Wet Ice
Concentration	5 mM
Product Line	BODIPY
Unit Size	Each

Ordering

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Thermo Fisher, G22183, Guanosine 5'-<i>O</i>-(3-Thiotriphosphate), BODIPY™ FL Thioester, Sodium Salt (BODIPY™ FL GTP-γ-S, Thioester)

Send an RFQ.

General

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