Thermo Fisher, H26425.MC, Hypericin, 98%

Name: Hypericin, 98%
Brand: Thermo Fisher
SKU: H26425.MC

Quantity: 100 mg, Unit Size: Each, Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis. This Thermo Scientific Chemicals brand product was originally part of t

Catalog Number: H26425.MC

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Category

Phosphatase Inhibitors

Pack Size100 mg

TagsChemicals Organic compounds Benzenoids Phenanthrenes and derivatives

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 100 mg
Unit Size: Each
General Description
• Hypericin is an anthraquinone derivative found in the yellow flower of Hypericum perforatum (also known as St. John's wort)
• This compound has the ability to inhibit protein kinase C, inducing photosynthesized apoptosisApplication
• It shows antibiotic and antiviral activities
• The antidepressant activity of this compound could be related to its ability to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine, gamma-aminobutyric acid (GABA), and L-glutamate
• Since this compound is able to inhibit the assembly and shedding of virus particles in infected cells, hypericin may also prevent the replication of encapsulated viruses
• It has been described that this compound can also exhibit anti-HIV and anticancer activities
• Hypericin also displays an effective phototoxic activity and is able to trigger apoptotic pathways, resulting in the formation of reactive oxygen species

Specifications

General

Beilstein	1917913
CAS	548-04-9
ChEBI	CHEBI:5835
Chemical Name or Material	Hypericin
EINECS Number	208-941-0
Formula Weight	504.44
Health Hazard 1	H302-H317
Health Hazard 2	<b>GHS H Statement</b><br />H301<br />Toxic if swallowed.
Health Hazard 3	P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
InChI Key	BTXNYTINYBABQR-UHFFFAOYSA-N
MDL Number	MFCD00016683
Melting Point	∼320°C (decomposition)
Merck Index	14,4863
Molecular Formula	C30H16O8
PubChem CID	5281051
RTECS Number	SF8472000
Recommended Storage	Store at -20°C
SMILES	CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
Sensitivity	Light sensitive
Solubility Information	Soluble in ethanol,dimethyl sulfoxide,methanol,acetone,ethylmethylketone,pyridine and sodium hydroxide. Insoluble in water.
Synonym	1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro 1,10,9,8-opqra perylene-7,14-dione

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Thermo Fisher, H26425.MC, Hypericin, 98%

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