Thermo Fisher, H26473.03, 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

Name: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%
Brand: Thermo Fisher
SKU: H26473.03

Quantity: 1 g, Unit Size: Each, AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation. This Thermo Scientific Chemicals brand

Catalog Number: H26473.03

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Category

Protein Purification Columns

TagsChemicals Organic compounds Sulfonyl halides

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 1 g
Unit Size: Each
ApplicationsAEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.SolubilitySoluble in water 50 mg/mL or 100% ethanol.NotesMoisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.

Specifications

General

UN Number
Beilstein	7604627
CAS	30827-99-7
Chemical Name or Material	4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
DOT Information	Hazard Class: 8; Packaging Group: III
Formula Weight	239.69
Health Hazard 1	H314-H500
Health Hazard 2	<b>GHS H Statement</b><br />H314-H318<br />Causes severe skin burns and eye damage.<br />Causes serious eye damage.
Health Hazard 3	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
IUPAC Name	4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride
InChI Key	WRDABNWSWOHGMS-UHFFFAOYSA-N
MDL Number	MFCD00132962
Melting Point	∼184°C (decomposition)
Molecular Formula	C8H11ClFNO2S
PubChem CID	186136
Recommended Storage	Store at -20°C
SMILES	C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl
Sensitivity	Moisture sensitive
Solubility Information	Soluble in water 50mg/mL or 100% ethanol.
Synonym	pefabloc
TSCA	No

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Thermo Fisher, H26473.03, 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

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