Thermo Fisher, J60148.LB0, Actinomycin D

Name: Actinomycin D
Brand: Thermo Fisher
SKU: J60148.LB0

Quantity: 5 mg, Unit Size: Each, Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth an

Catalog Number: J60148.LB0

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General

RTECS Number
Beilstein	605235
CAS	50-76-0
Chemical Name or Material	Actinomycin D
DOT Information	Transport Hazard Class: 6.1; Packaging Group: II; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
EINECS Number	200-063-6
Formula Weight	1255.4
Health Hazard 1	H300-H336-H373
Health Hazard 2	<b>GHS H Statement</b><br />H300-H360-H351<br /> Fatal if swallowed. <br />May damage fertility or the unborn child. <br />Suspected of causing cancer.
Health Hazard 3	P260-P264b-P270-P271-P301+P310-P304+P340-P312-P314-P330-P501c
IUPAC Name	2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,
InChI Key	RJURFGZVJUQBHK-HUZQGMAJSA-N
MDL Number	MFCD00005033
Melting Point	251°C to 253°C
Merck Index	14,2800
Molecular Formula	C62H86N12O16
PubChem CID	131954673

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Thermo Fisher, J60148.LB0, Actinomycin D

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