Thermo Fisher, J61491.03, Amphotericin B, Streptomyces nodosus

Name: Amphotericin B, Streptomyces nodosus
Brand: Thermo Fisher
SKU: J61491.03

Quantity: 1 g, Unit Size: Each, Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus. Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the l

Catalog Number: J61491.03

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Category

General Purpose Solvents

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 1 g
Unit Size: Each
General Description
• Amphotericin B is an antibiotic that has antifungal activity and is produced mainly by Streptomyces nodosusApplications
• It has antifungal activity against fungus caused by protozoan parasites of Leishmania genus by binding to an essential component of the fungal cell membrane and altering cell membrane permeability
• It can suppress bone marrow progenitor cells and induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro

Specifications

General

Beilstein	78342
CAS	1397-89-3
Chemical Name or Material	Amphotericin B
EINECS Number	215-742-2
Formula Weight	924.1
Health Hazard 1	H315-H319-H335
Health Hazard 2	<b>GHS H Statement</b><br />H315-H319-H335<br /> Causes skin irritation.<br />Causes serious eye irritation.<br />May cause respiratory irritation.
Health Hazard 3	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
IUPAC Name	(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
InChI Key	APKFDSVGJQXUKY-ZNVUZQDLSA-N
MDL Number	MFCD00877763
Merck Index	14,585
Molecular Formula	C47H73NO17
Name Note	<i>Streptomyces nodosus</i>
PubChem CID	134129663
RTECS Number	BU2625000
Recommended Storage	Keep cold

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Thermo Fisher, J61491.03, Amphotericin B, Streptomyces nodosus

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