Thermo Fisher, J62032.MC, Glimepiride

Name: Glimepiride
Brand: Thermo Fisher
SKU: J62032.MC

Quantity: 100 mg, Unit Size: Each, Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1

Catalog Number: J62032.MC

Pricing

Send an RFQ.

View RFQ List

Category

Bacterial Expression Systems

Pack Size100 mg

TagsChemicals Organic compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 100 mg
Unit Size: Each
ApplicationsGlimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker. Potent Kir6 (KATP) channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac Kir6 channels with an IC50 of 6.8 nM.SolubilitySoluble in DMSONotesStore in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Specifications

General

CAS	93479-97-1
Chemical Name or Material	Glimepiride
Color	White
Formula Weight	490.62
IUPAC Name	3-ethyl-4-methyl-N-{2-[4-({[(4-methylcyclohexyl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
InChI Key	WIGIZIANZCJQQY-UHFFFAOYSA-N
MDL Number	MFCD00878417
Melting Point	212°C to 215°C
Merck Index	14,4440
Molecular Formula	C24H34N4O5S
PubChem CID	3476
RTECS Number	UX9363950
Recommended Storage	Ambient temperatures
SMILES	CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CCC(C)CC2)C1=O
Solubility Information	Soluble in DMSO
Synonym	roname
TSCA	No
Molecular Weight (g/mol)	490.62
Physical Form	Powder
Quantity	100 mg
Unit Size	Each

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Thermo Fisher, J62032.MC, Glimepiride

Send an RFQ.

General

Notice

More from Thermo Fisher.

NaCl (5 M), RNase-free, 100 mL

Potassium Acetate (3 M), pH 5.5, RNase-free

SDS, 20% Solution, RNase-free

RNase A, DNase and protease-free (10 mg/mL)

More from Thermo Fisher.

NaCl (5 M), RNase-free, 100 mL

Potassium Acetate (3 M), pH 5.5, RNase-free

SDS, 20% Solution, RNase-free

RNase A, DNase and protease-free (10 mg/mL)