Thermo Fisher, J62104.MC, Sulindac Sulfide

Name: Sulindac Sulfide
Brand: Thermo Fisher
SKU: J62104.MC

Quantity: 100 mg, Unit Size: Each, It is also shown to inhibit growth and induce apoptosis in human prostate cancer cells through a COX-1 and COX-2 independent mechanism. Sulindac sulfide is an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of cyclooxygenase-2 in human colon cancer cells, and reduces tumor burden in adenomatous polyposis patients. Human endothelial cells, HMEC-1 were treated with Sulindac sulfide and the effect on cell surviva

Catalog Number: J62104.MC

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General

CAS	32004-67-4
Description	Yellow
EINECS Number	250-892-2
For Use With (Application)	Active metabolite of sulindac; inhibits cyclooxygenase-1
Form	Powder
Formula Weight	340.41g/mol
IUPAC Name	2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid
InChI Key	LFWHFZJPXXOYNR-RQZCQDPDSA-N
MDL Number	MFCD00869764
Melting Point	189°C to 191°C
Molecular Formula	C20H17FO2S
Quantity	100 mg
Recommended Storage	Ambient temperatures
SMILES	CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1
Solubility	Soluble in DMSO
Molecular Weight (g/mol)	340.41
Product Type	Signal Transduction Reagent
Unit Size	Each

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Thermo Fisher, J62104.MC, Sulindac Sulfide

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