Thermo Fisher, J62168.03, Amiloride hydrochloride dihydrate

Quantity: 1 g
Unit Size: Each
ApplicationsAmiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 μM. Amiloride • HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.SolubilitySoluble in water at 50mg/mlNotesStore in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.