Thermo Fisher, J62311.06, Berberine chloride

Name: Berberine chloride
Brand: Thermo Fisher
SKU: J62311.06

Quantity: 5 g, Unit Size: Each, Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accum

Catalog Number: J62311.06

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General

Beilstein	3836585
CAS	633-65-8
ChEBI	CHEBI:31271
Chemical Name or Material	Berberine chloride
Color	Yellow to Orange
EINECS Number	211-195-9
Formula Weight	371.82
InChI Key	VKJGBAJNNALVAV-UHFFFAOYSA-M
MDL Number	MFCD00011939
Molecular Formula	C20H18ClNO4
PubChem CID	12456
Recommended Storage	Keep cold
SMILES	COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
Solubility Information	Soluble in dimethyl sulfoxide (74mg/ml at 25°C),ethanol (<1mg/ml at 25°C),water (<1mg/ml at 25°C),and methanol.
Synonym	unii-uot4o1byv8
TSCA	Yes
Molecular Weight (g/mol)	371.817
Physical Form	Powder
Quantity	5 g
Unit Size	Each

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Thermo Fisher, J62311.06, Berberine chloride

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