Thermo Fisher, J62663.03, Tolmetin sodium salt dihydrate, 98+%

Name: Tolmetin sodium salt dihydrate, 98+%
Brand: Thermo Fisher
SKU: J62663.03

Quantity: 1 g, Unit Size: Each, Tolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 μM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Catalog Number: J62663.03

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Category

Modifying Enzymes

TagsChemicals Organic compounds Organooxygen compounds Carbonyl compounds Complex Ketones

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 1 g
Unit Size: Each
ApplicationsTolmetin Sodium is an anti-inflammatory, antirheumatic agent. It can inhibit aldo-keto reductases (e.g., IC50 = 2.39 µM for human aldose reductase), a family of enzymes that catalyze the NADPH-dependent reduction of carbonyl groups in a number of important steroid, metabolic, and prostanoid molecules. It is a beta-adrenergic blocker.SolubilitySoluble in waterNotesStore away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

General

CAS	64490-92-2
ChEBI	CHEBI:72014
Chemical Name or Material	Tolmetin sodium salt dihydrate
Color	White
EINECS Number	252-687-3
Formula Weight	315.30 (279.27 Anhydrous)
Health Hazard 1	H302-H315-H319
Health Hazard 2	<b>GHS H Statement</b><br />H302-H315<br /> Harmful if swallowed.<br />Causes skin irritation.
Health Hazard 3	P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c
IUPAC Name	sodium;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate;dihydrate
InChI Key	QQILXENAYPUNEA-UHFFFAOYSA-M
MDL Number	MFCD00150761
Merck Index	14,9518
Molecular Formula	C15H18NNaO5
PubChem CID	23677829
RTECS Number	UX9280000
Recommended Storage	Ambient temperatures
SMILES	CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].O.O.[Na+]
Solubility Information	Soluble in water
Synonym	sodium 1-methyl-5-p-toluoylpyrrole-2-acetate dihydrate
TSCA	No

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Thermo Fisher, J62663.03, Tolmetin sodium salt dihydrate, 98+%

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