Thermo Fisher, J62898.MA, U-73122, 95%

Name: U-73122, 95%
Brand: Thermo Fisher
SKU: J62898.MA

Quantity: 10 mg, Unit Size: Each, It is used as a phospholipase C, phospholipase A2, and 5-LO inhibitor. It is also determined that in SK-N-SH neuroblastoma cells, U-73122 inhibits agonist-induced down-regulation of muscarinic receptors. In addition, it is a useful tool to investigate receptor-mediated PI turnover in signal transduction. U-73122 is a potent inhibitor of human neutrophil adhesion to biological surfaces (IC50 = 50 nM) as well as adhesion-dependent granule exocytosis and oxidative

Catalog Number: J62898.MA

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General

Assay	≥99%
CAS	112648-68-7
Description	Off-white
For Use With (Application)	Inhibitor of phospholipase C activation and inhibits the down regulation of muscarinic receptors
Form	Crystalline solid
Formula Weight	464.65g/mol
IUPAC Name	1-(6-{[(1S,3aS,3bR,9bS,11aS)-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione
InChI Key	LUFAORPFSVMJIW-ZRJUGLEFSA-N
Molecular Formula	C29H40N2O3
Quantity	10 mg
Recommended Storage	Ambient temperatures
SMILES	COC1=CC=C2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCC2=C1)NCCCCCCN1C(=O)C=CC1=O
Solubility	Soluble in DMSO, ethanol, or DMF at approx. 0.5mg/ml; May require heating or overnight mixing; Insoluble in water
Synonym	1-[6-[((17beta)-3-Methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]pyrrole-2,5-dione
Molecular Weight (g/mol)	464.65
Product Type	Signal Transduction Reagent
Unit Size	Each

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Thermo Fisher, J62898.MA, U-73122, 95%

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