Thermo Fisher, J63361.14, 1,1-Dimethylbiguanide hydrochloride

Quantity: 25 g
Unit Size: Each
General Description • 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell