Thermo Fisher, J63895.14, Clotrimazole

Name: Clotrimazole
Brand: Thermo Fisher
SKU: J63895.14

Quantity: 25 g, Unit Size: Each, Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1. This Thermo Scientific Chemicals brand product was

Catalog Number: J63895.14

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Category

Alcohols

Pack Size25 g

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 25 g
Unit Size: Each
ApplicationsClotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.SolubilitySoluble in chloroform, DMSO, DMF and alcoholsNotesStore at room temperature. Incompatible with oxidizing agents.

Specifications

General

CAS	23593-75-1
ChEBI	CHEBI:3764
Chemical Name or Material	Clotrimazole
EINECS Number	245-764-8
Formula Weight	344.84
Health Hazard 1	H302-H315-H319
Health Hazard 2	<b>GHS H Statement</b><br />H302-H315-H319<br /> Harmful if swallowed.<br />Causes skin irritation.<br />Causes serious eye irritation.
Health Hazard 3	P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c
IUPAC Name	1-[(2-chlorophenyl)-diphenylmethyl]imidazole
InChI Key	VNFPBHJOKIVQEB-UHFFFAOYSA-N
MDL Number	MFCD00057220
Melting Point	141°C to 149°C
Merck Index	14,2417
Molecular Formula	C22H17ClN2
PubChem CID	2812
RTECS Number	NI4377000
Recommended Storage	Ambient temperatures
SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
Solubility Information	Soluble in chloroform, DMSO, DMF and alcohols
Synonym	1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole

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Thermo Fisher, J63895.14, Clotrimazole

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