Thermo Fisher, J66370.14, Nisin, 900 I.U./mg

Name: Nisin, 900 I.U./mg
Brand: Thermo Fisher
SKU: J66370.14

Quantity: 25 g, Unit Size: Each, Nisin, 900 I.U./mg is commonly used as a food preservative. It is also used as a selective agent in cell culture for the isolation of gram-negative bacteria, yeast, and molds. Nisin has been used in bioassays to study posttranslational modification. It binds and interferes with the permeability of the cytoplasmic membrane. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label informati

Catalog Number: J66370.14

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Category

Cell Culture Inserts

Pack Size25 g

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 25 g
Unit Size: Each
General Description
• Nisin is a broad-spectrum polycyclic peptide derived from and produced by Lactococcus lactis that shows antibacterial activity against gram-positive bacteria Nisin binds lipid II in the cell membrane. After binding it can insert into the membrane, creating a pore Nisin can efficiently inhibit the growth of gram-positive bacteria, and resistance is rarely observedApplication
• Nisin is commonly used as a selective compound in cell culture to isolate gram-negative bacteria, yeast, and molds (a type of fungus)
• It has been used in bioassays to study posttranslational modification
• This compound has the ability to bind and interfere with the permeability of the cytoplasmic membrane
• It is used to study the assembly and stability of nisin-lipid II pore complexes
• This compound is used in in vitro experiments to form targeted pores in cell membranes that are mediated by lipid II

Specifications

General

Unit Size
Boiling Point	2967°C
CAS	1414-45-5
Chemical Name or Material	Nisin
EINECS Number	215-807-5
Flash Point	>110°C (230°F)
Formula Weight	3354.06
InChI Key	NVNLLIYOARQCIX-OAXMGIFASA-N
MDL Number	MFCD00131724
Merck Index	14,6564
Molecular Formula	C143H230N42O37S7
Name Note	900 I.U./mg
PubChem CID	131847819
RTECS Number	QU3340000
Recommended Storage	Keep cold
SMILES	CCC(C)C1C(=O)NC(=C)C(=O)NC(C(=O)NC(CSCC(C(=O)N1)NC(=O)C(=CC)NC(=O)C(C(C)CC)N)C(=O)NC2C(SCC(NC(=O)CNC(=O)C3CCCN3C2=O)C(=O)NC(CCCCN)C(=O)NC4C(SCC(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC4=O)C)CC(C)C)CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC5C(
Solubility Information	Soluble in water
Storage Note 1	2° to 8°C
TSCA	No
Color	Brown
Molecular Weight (g/mol)	3354.09
Physical Form	Powder
Quantity	25 g
Type	Nisin

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Thermo Fisher, J66370.14, Nisin, 900 I.U./mg

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