Thermo Fisher, J66688.MB, Anhydrotetracycline hydrochloride

Name: Anhydrotetracycline hydrochloride
Brand: Thermo Fisher
SKU: J66688.MB

Quantity: 25 mg, Unit Size: Each, Anhydrotetracycline hydrochloride acts as a useful effector of tetracycline-dependent gene expression in bacterial expression systems. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Catalog Number: J66688.MB

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Category

Bacterial Expression Systems

Pack Size25 mg

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 25 mg
Unit Size: Each
General Description• Anhydrotetracycline hydrochloride is a degradation product derived from tetracycline hydrochloride. It acts as an effector of tetracycline-dependent gene expression in bacterial expression systems. In this system the transcription of genes is reversibly turned on/off in the presence of several compounds including, anhydrotetracycline hydrochloride.• This compound poorly binds to the 30S ribosomal subunit compared with its precursor, tetracycline.Applications• Anhydrotetracycline hydrochloride is commonly used in all fields of biology for control of transcription or translation processes• This compound has been used in laboratory experiments and shows lower antibacterial activity against Escherichia coli compared with tetracycline.

Specifications

General

Beilstein	4228856
CAS	13803-65-1
Chemical Name or Material	Anhydrotetracycline hydrochloride
Formula Weight	462.88
Health Hazard 1	H319-H361d
Health Hazard 3	P201-P202-P264b-P280i-P281-P305+P351+P338-P308+P313-P501c
IUPAC Name	hydrogen (2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-11,12a-dihydroxy-6-methyl-1,2,3,4,4a,5,12,12a-octahydrotetracene-1,3,12-trione chloride
InChI Key	FFZXKJVSZDKEMY-XGRJIHFXNA-N
MDL Number	MFCD00151453
Melting Point	220°C to 223°C
Molecular Formula	C22H23ClN2O7
PubChem CID	54710409
RTECS Number	QI7860000
Recommended Storage	Store at -20°C; Store under Argon
SMILES	[H+].[Cl-].CN(C)C1C2CC3=C(C(O)=C4C=CC=CC4=C3C)C(=O)C2(O)C(=O)\C(=C(\N)O)C1=O
Sensitivity	Moisture sensitive
Solubility Information	Soluble in ethanol, DMSO, or DMF
Storage Note 1	-30° to -10°C
TSCA	No
Color	Yellow
Molecular Weight (g/mol)	462.89

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Thermo Fisher, J66688.MB, Anhydrotetracycline hydrochloride

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