Thermo Fisher, J67364.XF, Doxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered

Name: Doxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered
Brand: Thermo Fisher
SKU: J67364.XF

Quantity: 1 mL, Unit Size: Each, It acts as an antitumor antibiotic agent that inhibits DNA topoisomerase II and acts as a DNA intercalator that inhibits nucleic acid synthesis and induces apoptosis. It reduces intracellular tau levels. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein. It is an is an inhibitor of AMPK, TERT and POLR. its fluorescent property has been exploited for the m

Catalog Number: J67364.XF

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General

CAS	25316-40-9
Chemical Name or Material	Doxorubicin hydrochloride
EINECS Number	246-818-3
Health Hazard 1	H319-H340-H350-H361
Health Hazard 2	<b>GHS H Statement</b><br />H350<br /> May cause cancer.
Health Hazard 3	P201-P202-P264b-P280i-P281-P305+P351+P338-P308+P313-P501c
IUPAC Name	hydrogen (8S,10S)-10-[(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy]-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione chloride
InChI Key	MWWSFMDVAYGXBV-FGBJBKNOSA-N
MDL Number	MFCD00077757,MFCD00077757,MFCD00941448
Molecular Formula	C27H30ClNO11
Name Note	10mg/mL in distilled water, sterile-filtered
PubChem CID	129626538
RTECS Number	QI9295900
Recommended Storage	Store at -20°C
SMILES	[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
Solubility Information	Fully miscible in water and soluble in 50 mM in DMSO,methanol and isotonic sodium chloride (>10mg/ml). Insoluble in chloroform,and ether.

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Thermo Fisher, J67364.XF, Doxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered

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