Thermo Fisher, J67389.MA, U-18666A, 95%

Name: U-18666A, 95%
Brand: Thermo Fisher
SKU: J67389.MA

Quantity: 10 mg, Unit Size: Each, Impaired trafficking of cholesterol to or from the endoplasmic reticulum (ER) has been implicated in many disease states including Neimann-Pick disease type C (NPC), Alzheimers disease and atherosclerosis. U-18666A is a cell permeable drug that inhibits cholesterol trafficking. It inhibits cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum (ER), but not cholesterol transport to the plasma membrane as demonstrated in many cell types

Catalog Number: J67389.MA

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General

Assay	95%
CAS	3039-71-2
Description	White to off-white
Form	Solid
Formula Weight	424.06
IUPAC Name	hydrogen 8-[2-(diethylamino)ethoxy]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one chloride
InChI Key	ICPRVJHNLABCSA-UHFFFAOYNA-N
Melting Point	195°C to 196.5°C
Molecular Formula	C25H42ClNO2
Quantity	10 mg
Recommended Storage	Keep cold
SMILES	[H+].[Cl-].CCN(CC)CCOC1CCC2=CCC3C4CCC(=O)C4(C)CCC3C2(C)C1
Solubility	Soluble in water at 10mg/ml
Synonym	3β-[2-(Diethylamino)ethoxy]androstenone hydrochloride
Molecular Weight (g/mol)	424.07
Product Type	U-18666A, 95%
Unit Size	Each

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Thermo Fisher, J67389.MA, U-18666A, 95%

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