Thermo Fisher, L08356.14, Triethyl methanetricarboxylate, 98%

Quantity: 25 g
Unit Size: Each
ApplicationsMethanetricarboxylates have been used as “blocked” malonic esters, restricting reaction with alkyl halides to monoalkylation. The unwanted carboxyl group can be removed by treatment with Na alkoxide, LDA or BCl3. Provides a useful 2-carbon chain extension method that adds to Michael acceptors under phase-transfer conditions. Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.SolubilityInsoluble in water.NotesStore away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.